Malegra, containing sildenafil citrate as its active ingredient, typically starts to show results within 30 to 60 minutes after ingestion. Here's a more detailed timeline of what to expect:
Onset of Action: Malegra is usually taken about 30 minutes to 1 hour before anticipated sexual activity. During this time, sildenafil citrate is absorbed into the bloodstream after oral ingestion.
Absorption and Peak Plasma Concentration: After ingestion, sildenafil citrate is rapidly absorbed in the gastrointestinal tract. Peak plasma concentrations are typically reached within 30 to 120 minutes, depending on individual factors such as metabolism, food intake, and the specific formulation of Malegra.
Response to Sexual Stimulation:
Malegra, like other phosphodiesterase type 5 (PDE5) inhibitors, requires sexual stimulation to be effective. Sexual arousal triggers the release of nitric oxide (NO) and initiates the biochemical cascade leading to an erection. Malegra enhances this natural response by inhibiting PDE5, prolonging the effects of NO, and promoting vasodilation in the penile arteries.
Erection Response: With sufficient levels of sildenafil citrate in the bloodstream and sexual stimulation, Malegra facilitates the physiological processes that lead to an erection. This includes improved blood flow to the penis, engorgement of the erectile tissues, and the ability to achieve and maintain a firm erection suitable for sexual activity.
Optimal Timing: To ensure optimal results, it's recommended to take Malegra as directed by your healthcare provider, typically about 30 minutes to 1 hour before engaging in sexual activity. Taking the medication on an empty stomach may lead to faster absorption and onset of action compared to taking it with a meal.
