Common manifestations include asymmetric arthritis of variable severity that tends to affect the lower extremities with sausage- shaped deformities of fingers or toes or both, constitutional symptoms, enthesitis, tendinitis, and mucocutaneous ulcers, including hyperkeratotic or crusted vesicular lesions keratoderma blennorrhagicum.
doxycycline uses Testing requires either collection of blood samples inside the isolator or removal of one or more mice from the isolator to obtain the samples.
