Delayed activation of BAX BAK and subsequent apoptosis upon BH3 mimetics treatment was thought to cause reduced BH3 mimetics efficacy by lifting the early apoptosis threshold in the absence of TP53
furosemide lasix FIG 40 illustrates a dose response analysis of chemical 542 using the G CSF reporter cell line G21 solid line and the MTT respiratory inhibition cytotoxicity assay dotted line