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The European patent EP2105164 is related to the composition of AFC-5128, a highly potent orally active P2X7 antagonist. A key advantage of the compound is its ability to cross the blood-brain barrier and target P2X7-expressing CNS-cells such as glia and oligodendrocyte cells which are linked to neurodegenerative processes. Affectis has shown that oral administration of AFC-5128 significantly reduces clinical scores and frequency of relapse in a mouse model of multiple sclerosis.Strong analgesic effects have also been observed in animal models of inflammatory and neuropathic pain. With these efficacy data available, Affectis is on track fo
yeezy 500 r filing an IND in 2012 for neuropathic pain and
yeezy 700 multiple sclerosis.The granted patent also covers the composition of further P2X7 antagonist compounds. Affectis has filed corresponding patent applications that are being processed in major markets such as the USA, Ja
new balance sneaker pan, China, among others.Dr. Manfred Ruediger, CEO of Affectis, commented, "The issuanc ISLAMABAD:Alternative Energy Development Board has issued Letters of Intent to 12 companies and sugar mills to generate 387 megawatts of
newbalance 530 elect
adidas campus beige ricity by 2018. According to official sources, out of 12 projects, six have already started generation, while others would be operational by 2018. The projects, which started
adidas velosamba generation in first phase, include Hamza Sugar Mill Limited Rahim Yar Khan, Layyah Sugar Mills Ltd, Alliance Sugar Mills Ltd Ghotki, Safina Sugar Mills Chiniot, Almoiz Industries Ltd Mianwali and Etihad Power Generation Rahim Yar Khan. Similarly, the projects which would start generation in the second phase include Chanar Energy Limited Faisalabad, RYK Energy Rahim Yar Khan, Shahtaj Sugar Mills Ltd Mandi Bahauddin, Sheikhoo Power Limited Muzafargarh, Indus Energy Ltd Rajanpur and Hamza Sugar Mills Unit-II.Published in The Express Tribune, April 5th, 2017.Like聽Business on Facebook, follow @TribuneBiz聽on Twitter to stay informed and join in the conversation.
